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Hypogen Inc 3d-qsar pharmacophore
3d Qsar Pharmacophore, supplied by Hypogen Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/3d+qsar+pharmacophore/3d+qsar+pharmacophore+models/pm40017298-61-7-14
Average 90 stars, based on 1 article reviews
3d-qsar pharmacophore - by Bioz Stars, 2026-10
90/100 stars

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Article Title: 3D-QSAR pharmacophore modeling, virtual screening, molecular docking, MD simulations, in vitro and in vivo studies to identify potential anti-hyperplasia drugs.
Article Snippet: Funding information National Natural Science Foundation of China, Grant/Award Number: 82273852 Abstract Psoriasis is a common immune-mediated skin condition characterized by aberrant keratinocytes and cell proliferation.. The purpose of this study was to explore the FDA-approved drugs by 3D-QSARpharmacophoremodel and evaluate their efficiency by in-silico, in vitro, and in vivo psoriasis animal model. A 3D-QSAR pharmacophore model was developed by utilizing HypoGen algorithm using the structural features of 48 diaryl derivatives with diverse molecular patterns.. The model was validated by a test set of 27 compounds, by cost analysis method, and Fischer’s randomization test.



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